Arkansas Post was founded in 1686 by Henri de Tonti at the site of a Quapaw Indian village named Osotouy near where the Arkansas River enters the Mississippi River. This place was where the first recorded Christian services occurred in Arkansas. The site became a strategic point for France, Spain, the United States, and the Confederate States at different times during its history.
On 17 April 1783 British Colonel James Colbert conducted a raid against Spanish forces controlling Arkansas Post as part of a small campaign against the Spanish on the Mississippi River. Colbert's Raid was the only American Revolutionary War battle fought in Arkansas, or anywhere west of the Mississippi.
In 1803 Arkansas Post became a part of the United States as part of the Louisiana Purchase. The post was selected as the first capital of the Arkansas Territory and became the center of commercial and political life in Arkansas. Prior to statehood the territorial capital was moved to Little Rock, Arkansas, and Arkansas Post lost much of its importance.